A nasal antihistamine stops Long Covid after an acute infection!
Image created by Gemini AI by Troy Roach (August 2025) This is HUGE if true! Data is impressive in a randomised trial ! TLDR summary: 1. Use the nasal spray daily... especially if you feel run down or like you are getting sick. 2. Definitely use it two times a day during and after an acute infection. 3. It might help with Long Covid and MCAS by reducing histamine, but it is probably not a cure. 4. Azelastine might be a useful alternative to chlorpheniramine. In a quick search, I see many options for Azelastine but strange pricing, but only one oral (not nasal) option for chlorpheniramine. 5. Both of these drugs have been around for decades so they are cheap and there is good safety data on them. 6. I have been using a different class of nasal spray the second half of my LC journey called Avamys (Flonase). These two can be used together and do different things. Flonase reduces inflammation while the studied spray is an antihistamine. If true, regular use ( many infecti...